AI and 'Zombie Cells' Could Revolutionise Breast Cancer Risk Prediction

AI technology predicts breast cancer risk by detecting "zombie cells," offering more accurate assessments and improving early detection for better treatment outcomes.

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A recent study from the University of Copenhagen has introduced a breakthrough in predicting breast cancer risk through advanced AI technology, specifically trained to detect “zombie cells” — damaged, senescent cells that may indicate a higher cancer risk. The research highlights how this innovation can improve cancer detection and treatment for women globally. Here’s a closer look at the findings and some related tips on staying proactive in breast health.

The Role of AI in Breast Cancer Detection

Breast cancer remains one of the leading causes of death worldwide, claiming over 670,000 lives in 2022 alone. Early detection is crucial in improving survival rates, but current risk assessment models, like the widely used Gail model, often miss key indicators that could help catch cancer earlier. The recent study published in The Lancet Digital Health introduces an AI-powered solution that could change this.

Researchers at the University of Copenhagen developed deep learning AI algorithms that analyze breast tissue biopsies. These algorithms are trained to identify senescent cells, often referred to as “zombie cells” due to their damaged state and irregular appearance. While these cells no longer divide, they remain metabolically active and can contribute to tumour development by promoting inflammation.

By focusing on the shape and irregularities of the cell nuclei in tissue samples, the AI technology was able to more accurately predict breast cancer risk than traditional clinical methods. The findings show that combining this AI model with current tools could significantly improve cancer risk assessments, potentially increasing the accuracy by up to five times.

How AI Helps Improve Treatment

The ability to detect and assess cancer risk earlier opens up new possibilities for treatment. According to Associate Professor Morten Scheibye-Knudsen, who led the study, this AI technology could enable healthcare providers to tailor screenings and treatments based on individual risk factors. This personalized approach would allow doctors to closely monitor high-risk patients through more frequent mammograms and biopsies while reducing unnecessary procedures for low-risk individuals.

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Moreover, the AI model is designed to work with standard biopsy samples, making it easier to implement on a global scale once fully developed.

Tips for Staying Proactive with Breast Health

While AI and advanced research are paving the way for better detection methods, staying proactive with your breast health remains vital. Here are some tips to consider:

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  • Regular screenings – Follow recommended guidelines for mammograms and breast screenings. Early detection can significantly improve treatment outcomes.

  • Self-exams – Performing monthly breast self-exams can help you detect any unusual changes early. Knowing your body is key to identifying potential issues.

  • Healthy lifestyle – Maintain a balanced diet, stay active, and manage stress. Research shows that a healthy lifestyle can reduce cancer risks.

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  • Family history – If breast cancer runs in your family, speak to your doctor about genetic testing and more personalized screening protocols.

A New Era in Cancer Prediction

Though it may take a few years before AI-based tools like this are widely available in clinics, the potential benefits are vast. This technology could revolutionize breast cancer care by offering more precise risk assessments and improving the way doctors screen and treat patients. The ability to predict cancer risk earlier through AI could ultimately save lives and reduce the emotional and financial burdens of late-stage cancer treatment.

In the meantime, staying informed and proactive about breast health remains the best approach to early detection.

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Written by

Pheona Ilagan